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SILEO® (dexmedetomidine oromucosal gel) is an oromucosal gel formulation of dexmedetomidine hydrochloride provided in a 3 mL syringe at a concentration of 0.1 mg/mL. Using the syringe, SILEO is easily administered between the cheek and gum, allowing for transmucosal absorption. Because SILEO is formulated to provide a low dose of dexmedetomidine, the dog remains calm, yet fully functional, and is able to interact normally with the family.

Practical for Owners
⦁ Calming without sedating, allowing for normal dog-owner interactions
⦁ Easy to administer at home, when needed
⦁ Works on its own without any other treatments or training

Relief for Patients
⦁ Quick onset of action
⦁ Supports early intervention for optimal effect on the quality of life of the dog⦁ 8

Confidence for Veterinarians
⦁ Proven to be safe and effective in a randomized, placebo-controlled clinical trial
⦁ An easy treatment for a challenging condition

References
8. Overall, K. Manual of Clinical Behavioral Medicine for Dogs and Cats. St. Louis, MO: Elsevier Health Sciences, 2013:650-654.
The product information provided in this site is intended only for residents of the United States. The products discussed herein may not have marketing authorization or may have different product labeling in different countries. The animal health information contained herein is provided for educational purposes only and is not intended to replace discussions with an animal healthcare professional. All decisions regarding the care of a veterinary patient must be made with an animal healthcare professional, considering the unique characteristics of the patient.
Sileo® is trademark owned by Orion Corporation Orion Pharma Animal Health. It is manufactured by Orion Corporation and distributed by Zoetis under license from Orion Corporation Orion Pharma Animal Health. ©2018 Zoetis Services LLC. All rights reserved. SIL-00015

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CYTOPOINT™ can help control itch and bring back the fun in life1
CYTOPOINT is an innovative new therapy that targets itch at its source to help relieve the signs of atopic dermatitis in dogs for a month or longer with a single injection.*
Cytopoint injection helps control itch for weeks
CYTOPOINT is prescribed to help reduce scratching, chewing, licking and biting at the skin. When the itch is controlled, the damaged skin can heal, so that you and your dog have a chance to enjoy the fun things in life again.2
Indication: CYTOPOINT aids in the reduction of clinical signs associated with atopic dermatitis in dogs.
*Repeat administration every 4 to 8 weeks as needed in the individual patient.1

References: 1. Data on file, Study Report No. C863R-US-12-018, Zoetis LLC. 2. Gonzales AJ, Humphrey WR, Messamore JE, et al. Interleukin-31: its role in canine pruritus and naturally occurring canine atopic dermatitis. Vet Dermatol. 2013;24(1):48-53. doi:10.1111/j.1365-3164.2012.01098.x.

The product information provided in this site is intended only for residents of the United States. The products discussed herein may not have marketing authorization or may have different product labeling in different countries. The animal health information contained herein is provided for educational purposes only and is not intended to replace discussions with an animal healthcare professional. All decisions regarding the care of a veterinary patient must be made with an animal healthcare professional, considering the unique characteristics of the patient.

All trademarks are the property of Zoetis Services LLC or a related company or a licensor unless otherwise noted.
© 2016 Zoetis Services LLC. All rights reserved. CYT-00089